Pretreatment with probenecid lowers both the natriuresis and hyperreninemia made by Bumex. This antagonistic influence of probenecid on Bumex natriuresis isn't resulting from a immediate action on sodium excretion but is probably secondary to its inhibitory effect on renal tubular secretion of bumetanide. So, probenecid should not be administered concurrently http://bomex86318.blogripley.com/550828/indicators-on-보맥스-you-should-know