Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors during the central anxious procedure, conolidine modulates alternate molecular targets. A Science Advancements review identified that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. ... https://whatisthebestconolidinesu28123.articlesblogger.com/60247604/conoldine-alternative-natural-pain-relief-no-further-a-mystery