In this article, we demonstrate that conolidine, a natural analgesic alkaloid Employed in conventional Chinese drugs, targets ACKR3, thus offering added evidence of a correlation concerning ACKR3 and suffering modulation and opening alternate therapeutic avenues to the procedure of Long-term soreness. The primary asymmetric complete synthesis of conolidine was https://epicurusf914dxt0.wikienlightenment.com/user